The system, called Nanoparticle Induced Circuit Excitation (NICE), uses engineered nanoparticles attached to specific cells; when exposed to radiofrequency waves, the particles heat up and activate temperature-sensitive channels such as the TRPV1 protein, triggering responses like gene activation, protein production, hormone release, or neuron firing.
In mouse experiments, researchers used the method to make implanted cells release insulin and lower blood sugar without surgery, and also tested it on brain cells tied to appetite and dopamine signaling, as well as engineered stem cells.
The patent lists potential treatments for diabetes, Parkinson's disease, chronic pain, stroke, and hormone, immune, and neurological disorders.
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